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Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04533","func":"F0201","targ":"T002","compound":"D1390: Caffeine","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"> 400 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04534","func":"F0201","targ":"T002","compound":"D0325: Capsaicin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"15.7 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04535","func":"F0201","targ":null,"compound":"D1375: Carbamazepine","paper":"36","func_act":"increase","targ_act":"","dose":"170.8 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04536","func":"F0201","targ":"T002","compound":"D1391: Cefixime","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"216.8 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04537","func":"F0201","targ":"T002","compound":"D1392: Chlorambucil","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"140.9 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04538","func":"F0201","targ":"T002","compound":"D0259: Ciprofloxacin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04539","func":"F0201","targ":"T002","compound":"D1393: Clodronate","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"227.2 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04540","func":"F0201","targ":"T002","compound":"D0422: Clotrimazole","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04542","func":"F0201","targ":"T002","compound":"D0859: curcumin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"> 200 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04545","func":"F0201","targ":"T002","compound":"D0036: Daunorubicin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"10.9 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04546","func":"F0201","targ":"T002","compound":"D0871: dexamethasone valerate","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"> 200 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04656","func":"F010401","targ":null,"compound":"D0116: Tamoxifen","paper":"306","func_act":"Decrease","targ_act":"","dose":"100 µM","time":"1 hour","method":"High-content screening assay","species":"Human","animal_model":"HepG2","criteria":"MEC","result":true},{"rec_id":"RC04657","func":"F010401","targ":null,"compound":"D0124: Troglitazone","paper":"306","func_act":"Decrease","targ_act":"","dose":"5 µM","time":"1 hour","method":"High-content screening assay","species":"Human","animal_model":"HepG2","criteria":"MEC","result":true},{"rec_id":"RC04547","func":"F0201","targ":"T002","compound":"D0262: Diazoxide","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04548","func":"F0201","targ":"T002","compound":"D0038: Diclofenac","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"29.8 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04549","func":"F0201","targ":"T002","compound":"D0040: Diflunisal","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04552","func":"F0201","targ":"T002","compound":"D0043: Doxorubicin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04555","func":"F0201","targ":null,"compound":"D0470: erlotinib","paper":"36","func_act":"increase","targ_act":"","dose":"17.4 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04559","func":"F0201","targ":"T002","compound":"D0417: Fluconazole","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"186.6 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04560","func":"F0201","targ":"T002","compound":"D0057: Flufenamic Acid","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04561","func":"F0201","targ":"T002","compound":"D0062: Flutamide","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04563","func":"F0201","targ":"T002","compound":"D0440: gefitinib","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04564","func":"F0201","targ":"T002","compound":"D0951: genistein","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04566","func":"F0201","targ":"T002","compound":"D0266: Glimepiride","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04567","func":"F0201","targ":"T002","compound":"D0268: Gossypol","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04569","func":"F0201","targ":"T002","compound":"D0065: Ibuprofen","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"132.1 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04570","func":"F0201","targ":"T002","compound":"D1377: Imatinib","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04571","func":"F0201","targ":null,"compound":"D0461: imipramine","paper":"36","func_act":"increase","targ_act":"","dose":"18.3 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04572","func":"F0201","targ":"T002","compound":"D0069: Indomethacin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04573","func":"F0201","targ":"T002","compound":"D0071: Isoniazid","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04574","func":"F0201","targ":"T002","compound":"D0073: Ketoconazole","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"2.9 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04658","func":"F010401","targ":null,"compound":"D1379: atorvastatin","paper":"306","func_act":"Decrease","targ_act":"","dose":"50 µM","time":"1 hour","method":"High-content screening assay","species":"Human","animal_model":"HepG2","criteria":"MEC","result":true},{"rec_id":"RC04659","func":"F010401","targ":null,"compound":"D0021: Cerivastatin","paper":"306","func_act":"Decrease","targ_act":"","dose":"10 µM","time":"1 hour","method":"High-content screening assay","species":"Human","animal_model":"HepG2","criteria":"MEC","result":true},{"rec_id":"RC04660","func":"F010401","targ":null,"compound":"D0945: fluvastatin","paper":"306","func_act":"Decrease","targ_act":"","dose":"10 µM","time":"1 hour","method":"High-content screening assay","species":"Human","animal_model":"HepG2","criteria":"MEC","result":true},{"rec_id":"RC04575","func":"F0201","targ":"T002","compound":"D0075: Lamivudine","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"317.4 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04576","func":"F0201","targ":null,"compound":"D0076: Lidocaine","paper":"36","func_act":"increase","targ_act":"","dose":"188.2 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04577","func":"F0201","targ":"T002","compound":"D0364: Lonidamine","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04578","func":"F0201","targ":"T002","compound":"D0467: lovastatin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"6.2 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04579","func":"F0201","targ":"T002","compound":"D1299: lumiracoxib","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"12 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04580","func":"F0201","targ":"T002","compound":"D0192: Manganese","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"> 400 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04581","func":"F0201","targ":"T002","compound":"D0078: Mefenamic acid","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04583","func":"F0201","targ":"T002","compound":"D0080: Metformin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"351.8 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04587","func":"F0201","targ":"T002","compound":"D0083: Mitomycin","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04588","func":"F0201","targ":"T002","compound":"D0084: Mitoxantrone","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false},{"rec_id":"RC04593","func":"F0201","targ":"T002","compound":"D0091: Nicotine","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"312 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04594","func":"F0201","targ":"T002","compound":"D1015: nifuroxazide","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"3.7 µM","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":true},{"rec_id":"RC04596","func":"F0201","targ":"T002","compound":"D0092: Nimesulide","paper":"36","func_act":"decrease","targ_act":"inhibit","dose":"ND","time":"60 mins","method":"Oxygen consumption was monitored with 50nM MitoXpress ( an oxygen-sensitive phosphorescent dye) using a spectrofluorimeter (Tecan Infinite 200; λExcitation 380nm; λEmission 650nm). Oligomycin A (1µM) was used as 100% baseline for complex II inhibition.","species":"mouse","animal_model":"liver mitochondria","criteria":"EC20","result":false}]}