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2021 MitoTox | (CC BY-NC 4.0)
Compound

D0277 | Mdivi-1

Molecular Formula C15H10Cl2N2O2S
Molecular Weight 353.2
Structure
Description a cell-permeable selective dynamin-related protein 1 (Drp1) inhibitor; a mitochondrial division/mitophagy inhibitor ; quinazolinone derivative;

Toxicity Dose Time Species Model Method Action Positive criterion Reference
FISSION 248
FISSION inhibitor 296

Target Dose Time Species Model Method Action Positive criterion Reference
Dynamin-1-like protein 248
Dynamin-1-like protein inhibitor 296


  • 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone 3-(2,4-dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4 (1h)-quinazolinone
    3-(2,4-dichloro-5-methoxyphenyl)-2-mercaptoquinazolin-4(3H)-one 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one
    338967-87-6 6L-585S A14316
    AK341040 AKOS005095924 AKOS026750256
    AOB6944 BCP08531 BS0305
    Bionet1_002447 C15H10Cl2N2O2S CHEMBL1449747
    CS-2462 CTK8E8741 DTXSID50396940
    EC-000.2482 EX-A684 FT-0700293
    HMS2300O14 HMS3653M13 HMS575G09
    HY-15886 J-019365 KS-00000LFE
    LQT-B00679 M3108 MLS000326208
    Mdivi 1 Mdivi-1 Mdivi-1, >=98% (HPLC), powder
    Mdivi1 Mitochondrial division inhibitor 1 Oprea1_325089
    RT-013669 SCHEMBL17329297 SCHEMBL5025872
    SMR000170329 SW220178-1 Y1878
    ZINC100080849 s7162

    CAS Number 338967-87-6
    PubChem Compound 3825829
    ChemSpider 3052036