F020105 | DNP-uncoupled respiration


Function of mitochondria >> Respiration >> DNP-uncoupled respiration

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Nitrofurantoin 0.005mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
Nitrofurantoin 1 mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
Nitrofurantoin 0.05mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
Nitrofurantoin 1 mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
Nitrofurantoin 0.05mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
nitrofurazone 1mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
nitrofurazone 1mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13
Nitrofurantoin 1 mM mouse; C57B/6J liver mitochondria Measurement of oxygen uptake decrease Positive p < 0.05 13