Search References Drug Actions/Targets About Access data Feedback
Sign In
[email protected]
2021 MitoTox | (CC BY-NC 4.0)

F0703 | Autophagy

GO:0006914
Cell death >> Autophagy

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Rotenone 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
nocodazole 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
Chloroquine 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
Brefeldin A 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
Tunicamycin 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
thapsigargin 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
Gingerol 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
Staurosporine 1µM overnight HeLa cells Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay induce Positive >2 fold increase 277
Bafilomycin A1 inhibit Positive 200

T416. Serine/threonine-protein kinase mTOR