Drug
D0491 | clemastine
D
R
R06AA54 Clemastine, combinations
[R06AA] Aminoalkyl ethers
[R06A] ANTIHISTAMINES FOR SYSTEMIC USE
[R06] ANTIHISTAMINES FOR SYSTEMIC USE
[R] Respiratory system
R06AA04 Clemastine
[R06AA] Aminoalkyl ethers
[R06A] ANTIHISTAMINES FOR SYSTEMIC USE
[R06] ANTIHISTAMINES FOR SYSTEMIC USE
[R] Respiratory system
D04AA14 Clemastine
[D04AA] Antihistamines for topical use
[D04A] ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
[D04] ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
[D] Dermatological drugs
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| UNCOUPLING | rat | isolated liver mitochondria | measurements of mitochondrial respiration; RST inhibition assay, RST uncoupling assay; IC 50ratio of glucose/galactose assay | increase | 53 | |||
| (+)-(2R)-2-(2-(((R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine | (+)-(2R)-2-[2-[[(R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine | (2R)-2-(2-{[(1R)-1-(4-chlorophenyl)-1-phenylethyl]oxy}ethyl)-1-methylpyrrolidine |
| (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine | (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine;fumarate | (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine |
| (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine | (E)-2-butenedioate;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine | (E)-but-2-enedioate;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine |
| (E)-but-2-enedioate;(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine; | (R)-2-(2-((R)-1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine | (R)-2-[2-[(R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine |
| 15686-51-8 | 2(R)-[2-[(1R)-(4-Chlorophenyl)-1-phenyl-ethoxy]ethyl-1-methylpyrrolidine | 2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine |
| 2-(2-(4-Chlor-alpha-methylbenzhydryloxy)ethyl)-1-methylpyrrolidin | 686C518 | 95QN29S1ID |
| AB00053766-06 | AB00053766-07 | AB00053766_08 |
| AB00053766_09 | API0009140 | BDBM50253157 |
| BDBM94606 | BIDD:GT0391 | BPBio1_000300 |
| BRD-K30240666-051-05-0 | BRD-K30240666-051-08-4 | BSPBio_000272 |
| BSPBio_002045 | C-23710 | C21H26ClNO |
| CAS-14976-57-9 | CC-25901 | CHEBI:3738 |
| CHEMBL1626 | Clemastina | Clemastina [INN-Spanish] |
| Clemastine [USAN:BAN] | Clemastine [USAN:INN:BAN] | Clemastinum |
| Clemastinum [INN-Latin] | DB00283 | DL-247 |
| DTXSID2022832 | DivK1c_000285 | FT-0772929 |
| GTPL6063 | HMS2089I22 | HS 592 |
| HS-592 | IDI1_000285 | KBio1_000285 |
| KBio3_001265 | KBioGR_001570 | KSC-315-033- |
| KUC112480N | LS-137531 | Lopac-C-8903 |
| M192 | MLS002154260 | Meclastin |
| Meclastine | Mecloprodin | NCGC00015281-01 |
| NCGC00016710-01 | NCGC00016710-02 | NCGC00025168-01 |
| NINDS_000285 | Prestwick0_000306 | Prestwick1_000306 |
| Prestwick2_000306 | Prestwick3_000306 | Pyrrolidine, 2-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methyl-, (R-(R*,R*))- |
| Q418145 | SBI-0052796.P003 | SCHEMBL4178 |
| SMR001233520 | SPBio_000817 | SPBio_002491 |
| Spectrum2_000689 | Spectrum3_000353 | Spectrum4_000955 |
| Spectrum5_001520 | Tavist (*Fumarate*) | Tocris-1453 |
| UNII-95QN29S1ID | YNNUSGIPVFPVBX-NHCUHLMSSA-N | ZINC402830 |
| cid_45479735 | clemastine |