MITOTOX

Compound

D0517 | TDS

Properties

Molecular Formula	X
Molecular Weight	X
Structure
Trade names	tridecyl stigmatellin
Description	complex I inhibitors; Type C—quinol antagonists

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
ELECTRON TRANSPORT CHAIN						affect		53
ELECTRON TRANSPORT CHAIN	40 nmol/mg		bovine	mitochondria	NADH–Q	decrease	IC50	99

Targets

Target	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
NADH:ubiquinone reductase	40 nmol/mg		bovine	mitochondria	NADH–Q	inhibitor	IC50	99
quinol						antagonist		53

Indications Source: SIDER

References