F020201 | Generation of lactate
GO:0019244
map00620
R-HSA-70268
Function of mitochondria >> Pyruvate metabolism >> generation of lactate
Function of mitochondria >> Pyruvate metabolism >> generation of lactate
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Ciprofloxacin | Increase | Positive | 307 | ||||||
| Metformin | 5mM | 30 minutes | mouse; C57BL/6J | isolated skeletal muscle mitochondria | Meassurement of lactate concentration | increase | Positive | p < 0.05 | 172 |