Function of mitochondria >> Glucose metabolism >> Glycolysis >> ECAR

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
Tolcapone	3.7 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Entacapone	100 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Nilutamide	79 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Flutamide	> 100 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Chlorpromazine	> 300 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Diflunisal	30 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Benoxaprofen	> 100 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Troglitazone	> 100 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Ciglitazone	> 100 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Troglitazone	10 μM	2 minutes	feline	cardiomyocytes	Measurement of ECAR	increase	Positive	EC50	7
Ciglitazone	10 μM	2 minutes	feline	cardiomyocytes	Measurement of ECAR	increase	Positive	EC50	7
Rosiglitazone	> 100 μM	2 minutes	feline	cardiomyocytes	Measurement of ECAR	increase	Positive	EC50	7
buformin	25 μM	24 hours	human	HepG2 cells	Measurement of ECAR	increase	Positive	p < 0.001	15
Phenformin	25 μM	24 hours	human	HepG2 cells	Measurement of ECAR	increase	Positive	p < 0.001	15
Rotenone	371±58 nM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Antimycin A	100±20 nM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
Oligomycin	1.1±0.23 μM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
FCCP	141±20 nM	2 minutes	human	HepG2	Measurement of ECAR	increase	Positive	EC50	7
2-Deoxy-D-glucose	150 mM	2 minutes	human	HepG2	Measurement of ECAR	decrease	Positive	EC50	7