F021203 | ATP level
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Amitriptyline | Positive | 197 | |||||||
| Desipramine | Positive | 197 | |||||||
| Troglitazone | >25 µM | 1 and 2 hr | HepG2 cells | Cellular ATP concentrations were measured with a ATP Bioluminescent Somatic Cell Assay Kit | decrease | Positive | 332 | ||
| Troglitazone | human | hepatocytes | ATP bioluminescence assay | decrease | Positive | 226 | |||
| Diazepam | 150μg/ml | 2hr | PE cells | luciferin-luciferase method | decrease | Positive | 293 | ||