| MG-132 |
20 μM |
24 hr |
rat |
PC12 cells |
Measurement of cytochrome c release using a solid-phase, enzyme-linked immunosorbent assay kit for the detection of cytochrome c. |
increase |
Positive |
|
289 |
| Flufenamic Acid |
70 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Tolfenamic Acid |
75 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Mefenamic acid |
277 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Meloxicam |
245 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Sudoxicam |
282 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Piroxicam |
598 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Diflunisal |
79 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Diclofenac |
197 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Sulindac sulfide |
59 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
| Nimesulide |
21 |
24hr |
rat |
hepatocytes |
cytochrome c release (anti-cytochrome c antibody ) |
induce |
Positive |
AC50 (μM) |
40 |
