T221 Source: Uniprot
proteinMitochondrial brown fat uncoupling protein 1
(UCP 1)
Ion channel
| Full Name | Mitochondrial brown fat uncoupling protein 1 |
|---|---|
| Protein Names | Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Solute carrier family 25 member 7) (Thermogenin) |
| Subcellular Location | Mitochondrion inner membrane Multi-pass membrane protein |
| Uniprot Accession | P25874 |
| Uniprot Name | UCP1_HUMAN |
| Gene symbol | UCP1 |
| Gene Name | Uncoupling protein 1 |
| Ensembl | ENSG00000109424 |
| Compound | Dose | Time | Species | Model | Method | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| AJ-9677 | Positive | 204 | ||||||
| AJ-9677 | 0.1 mg/kg body weight | dog | adipocytes | Western blot (a primary antibody against rat UCP1 ); Oxygen consumption of isolated adipocytes was measured polarographically with a Clark-style oxygen electrode | Positive | 214 | ||