T260 Source: Uniprot

enzymeProhibitin-2 (D-prohibitin)
Receptor Repressor
Full Name Prohibitin-2
Protein Names Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Subcellular Location Cell membrane Cytoplasm Mitochondrion inner membrane Nucleus [Isoform 1]: Mitochondrion inner membrane [Isoform 2]: Mitochondrion inner membrane
Uniprot Accession Q99623
Uniprot Name PHB2_HUMAN
Gene symbol PHB2
Gene Name Prohibitin 2
Ensembl ENSG00000215021

Compound Dose Time Species Model Method Result Positive criterion Reference
Xanthohumol 30μM 24hr MCF7 cells using the MAP1LC3II/I ratio to monitor the autophagic flux; quantifiedPMPCB staining Positive 283