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T387001

moleculesuperoxide (O2s)

Reactive oxygen species >>
Full Name superoxide

Compound Dose Time Species Model Method Result Positive criterion Reference
Nimesulide 1 mM rat; Sprague-Dawley Crl:CD (SD) BR lung microsomes adrenochrome assay (Misra and Fridovich, 1972) Positive p < 0.05 11
Paraquat 10 mM yeast; EG103 (Wild-type) mitochondria Measurement of superoxide anion Negative 14
Paraquat 10 mM yeast; EG103 (Wild-type) mitochondria Measurement of superoxide anion; Used ethanol (5 mM) as substrate Negative 14
Paraquat 10 mM yeast; EG110 (MnSOD knock-out) mitochondria Measurement of superoxide anion; Used ethanol (5 mM) as substrate Positive 14
Paraquat 10 mM yeast; EG103 (Wild-type) mitochondria Measurement of superoxide anion; Used ethanol (5 mM) as substrate Positive 14
Paraquat 10 mM yeast; EG103 (Wild-type) mitochondria Measurement of superoxide anion; Used ethanol (5 mM) as substrate; Used FCCP (1μm) as uncoupler Negative 14
Paraquat 1 mM 10 minutes rat isolated heart mitochondria Measurement of superoxide anion; Used glutamate/malate (5 mM) as substrate Positive 14
Paraquat 1 mM 10 minutes rat isolated heart mitochondria Measurement of superoxide anion; Used glutamate/malate (5 mM) as substrate; Used FCCP (1μm) as uncoupler Negative 14
Paraquat 0.1 mM 10 minutes rat isolated heart mitochondria Measurement of superoxide anion; Used succinate (5 mM) as substrate Positive 14
Paraquat 1 mM 10 minutes rat isolated heart mitochondria Measurement of superoxide anion; Used succinate (5 mM) as substrate; Used FCCP (1μm) as uncoupler Negative 14
Paraquat 0.1 mM 10 minutes rat isolated heart mitochondria Measurement of superoxide anion; Used succinate (5 mM) as substrate; Used rotenone (4μm) as inhibiter Negative 14

F05. Oxidative stress