Compound	Dose	Time	Species	Model	Method	Result	Positive criterion	Reference
Manganese	0.1–10 μM			Sprague Dawley rat astrocytes and microglia cell culture		Positive		242
Metformin	500 μM	24 hours	human	hepatocytes	Measurement of mitochondrial membrane potential	Negative		15
Metformin	1 mM	24 hours	human	hepatocytes	Measurement of mitochondrial membrane potential	Positive		15
Metformin	2 mM	24 hours	human	hepatocytes	Measurement of mitochondrial membrane potential	Positive		15
buformin	75 μM	24 hours	human	hepatocytes	Measurement of mitochondrial membrane potential	Positive		15
Phenformin	12.5 μM	24 hours	human	hepatocytes	Measurement of mitochondrial membrane potential	Positive		15

F05. Oxidative stress
F050501. antioxidant production