Function of mitochondria >> Lipid metabolism >> lipid peroxidation

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
amphotericin B	2.5mg/ml		Aspergillus fumigatus		the formation of MDAs by antifungal drug-derived ROS in A. fumigatus was determined using the thiobarbituric acid (TBA) assay.	induce	Positive		304
Aluminium	100 mg/kg in drinking water daily for six weeks		Wistar rats				Positive		242
Terbinafine	4mg/ml		Aspergillus fumigatus		lipid peroxidation using the thiobarbituric acid assay	induce	Positive		304
itraconazole	4mg/ml		Aspergillus fumigatus		lipid peroxidation using the thiobarbituric acid assay	induce	Positive		304
amphotericin B	2.5mg/ml		Aspergillus fumigatus		mitochondrion-specific lipid peroxidation probe MitoPerOx	induce	Positive		304
Terbinafine	4mg/ml	3min, 5min, 15min	Aspergillus fumigatus		mitochondrion-specific lipid peroxidation probe MitoPerOx	induce	Positive		304
itraconazole	4mg/ml		Aspergillus fumigatus		mitochondrion-specific lipid peroxidation probe MitoPerOx	induce	Positive		304
Chlorpyrifos	30–50 μM			PC12 cell line	we measured the concentration malondialdehyde (MDA) to indicate formation of lipid peroxides		Positive		242
Paraquat	10 mg/kg/week intraperitoneal (i.p.)	3weeks	C57BL/6 mice				Positive		242