Database
User
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| MG-132 | 20 μM | 6 hr | HeLa cells | The cells were stained with MitoTracker Green FM and MitoSOX Red dyes followed by image acquisition on a confocal microscope. | induce | Positive | 291 | ||
| Niclosamide | 1, 5, and 10 uM | 3 hr (1.5-6hr) | HeLa/mito-YFP | fluorescence microscope | induce | Positive | 294 | ||
| Diazepam | 140μg/ml | 16hr | PE cells | Energy-dependent accumulation of ethylrhodamine ; Electron micrographs of ultrathin sections | induce | Positive | 293 | ||
| P110 | 1 µM | 30min | Cultured SH-SY5Y cells incubated with MPP+ (2 mM, for 4 hours) or CCCP (5 µM, for 30 minutes). The cells were then stained with anti-Tom20 antibody (green) and Hoechst stain. | microscopy images | inhibit | Positive | 310 | ||
| BGP-15 | 50 μM | 4hr | WRL-68 cells | mERFP-labeled WRL-68 cells | reduce | Positive | 297 | ||
| H2O2 | 10 μmol/10E7 cells | 4-6hr | C2C12 mouse | muscle myoblasts | detected by either MitoTracker Red staining, or by mERFP transfection | induce | Positive | 297 | |