Organization of mitochondria >> Shape >> megamitochondria

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
Hydrazine	2 mM	22-24 h		primary culture rat hepatocytes, RL-34(JCRB 0247), COS-1(JCRB 9082) IAR-20(JCRB 0610)		induce	Positive		292
H2O2	0.2mM	22hr		rimary culture rat hepatocytes, RL-34,COS-1, IAR-20		induce	Positive		292
Chloramphenicol	200-300µg/ml	22hr		primary culture rat hepatocytes, RL-34,COS-1, IAR-20		induce	Positive		292
Ethidium Bromide	200-300 µg/ml, 2	22h		RL-34, COS-1, IAR-20L cells (mouse fibrob-lasts)		induce	Positive		292
Erythromycin	200 µg/ml	22 h		primary culture rat hepatocytes, RL-34,COS-1, IAR-20		induce	Positive		292
Indomethacin	0.3-0.5 mM	22 h		primary culture rat hep-atocytes, RL-34,COS-1, IAR-20		induce	Positive		292
Ethanol	12.5-500 mM	5min	rat	cardiac myocytes		induce	Positive		292
Ethanol	1-3%	6hr		RL-34		induce	Positive		292