T021002 Source: Uniprot
protein subunitCarnitine O-palmitoyltransferase 1, muscle isoform
(CPT-1B)
Transferase
Acyltransferase
carnitine palmitoyltransferases I >>
| Full Name | Carnitine O-palmitoyltransferase 1, muscle isoform |
|---|---|
| Protein Names | Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein) |
| Subcellular Location | Mitochondrion outer membrane Multi-pass membrane protein |
| EC numbers | 2.3.1.21 |
| Uniprot Accession | Q92523 |
| Uniprot Name | CPT1B_HUMAN |
| Gene symbol | CPT1B |
| Gene Name | Carnitine palmitoyltransferase 1B |
| Ensembl | ENSG00000205560 |
| Compound | Dose | Time | Species | Model | Method | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| aminocarnitine | >100 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Negative | IC50 (μM) | 333 | |
| palmitoylaminocarnitine | 21.7 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Positive | IC50 (μM) | 333 | |
| ST1326 | 5.4 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Positive | IC50 (μM) | 333 | |
| ST2425 | 85.3 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Positive | IC50 (μM) | 333 | |
| Trimetazidine | >100 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Negative | IC50 (μM) | 333 | |
| Perhexiline | >100 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Negative | IC50 (μM) | 333 | |
| Amiodarone | >100 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Negative | IC50 (μM) | 333 | |
| Oxfenicine | >100 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Negative | IC50 (μM) | 333 | |
| oxfenicine metabolite | 60.3 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Positive | IC50 (μM) | 333 | |
| RO-25-0187 | 0.16 | human/rat | recombinant Pichia pastoris Membrane Preparations | spectrophotometric assay with DTNB | Positive | IC50 (μM) | 333 | |