T021002 Source: Uniprot

protein subunitCarnitine O-palmitoyltransferase 1, muscle isoform (CPT-1B)
Transferase Acyltransferase
carnitine palmitoyltransferases I >>
Full Name Carnitine O-palmitoyltransferase 1, muscle isoform
Protein Names Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein)
Subcellular Location Mitochondrion outer membrane Multi-pass membrane protein
EC numbers 2.3.1.21
Uniprot Accession Q92523
Uniprot Name CPT1B_HUMAN
Gene symbol CPT1B
Gene Name Carnitine palmitoyltransferase 1B
Ensembl ENSG00000205560

Compound Dose Time Species Model Method Result Positive criterion Reference
aminocarnitine >100 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Negative IC50 (μM) 333
palmitoylaminocarnitine 21.7 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Positive IC50 (μM) 333
ST1326 5.4 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Positive IC50 (μM) 333
ST2425 85.3 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Positive IC50 (μM) 333
Trimetazidine >100 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Negative IC50 (μM) 333
Perhexiline >100 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Negative IC50 (μM) 333
Amiodarone >100 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Negative IC50 (μM) 333
Oxfenicine >100 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Negative IC50 (μM) 333
oxfenicine metabolite 60.3 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Positive IC50 (μM) 333
RO-25-0187 0.16 human/rat recombinant Pichia pastoris Membrane Preparations spectrophotometric assay with DTNB Positive IC50 (μM) 333