Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
Melittin	5μM and 16μM		bovine	bovine heart MF1-ATPase			Positive	IC50	170
Enterostatin							Positive		170
ethyldimethylaminopropyl carbodiimide	13 mol of EDC/mol F1 (EF1-ATPase)						Positive	95% inhibition	170
1,5-difluoro-2,4-dinitrobenzene							Positive		170
NBD-Cl							Positive		170
lumiracoxib							Positive		197
buformin	62.5 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	p < 0.001	15
buformin	62.5 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	p < 0.001	15
Phenformin	62.5 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	p < 0.001	15
Phenformin	62.5 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	p < 0.001	15
Metformin	657 μM	24 hours	human	hepatocytes	Assay of Cellular ATP Content	decrease	Positive	IC50	15
buformin	26.1 μM	24 hours	human	hepatocytes	Assay of Cellular ATP Content	decrease	Positive	IC50	15
Phenformin	11.7 μM	24 hours	human	hepatocytes	Assay of Cellular ATP Content	decrease	Positive	IC50	15
Metformin	1430 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	IC50	15
buformin	43.7 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	IC50	15
Phenformin	12.9 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	IC50	15
Metformin	> 2000 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	IC50	15
buformin	> 500 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	IC50	15
Phenformin	> 500 μM	24 hours	human	HepG2 cells	Assay of Cellular ATP Content	decrease	Positive	IC50	15
Diclofenac	250 μmol/L	24 hours	rat	hepatocytes	Assay of Cellular ATP contents; Assay of LDH leakage	decrease	Positive	p < 0.01	6
Diclofenac	500 μmol/L	24 hours	rat	hepatocytes	Assay of Cellular ATP contents; Assay of LDH leakage	decrease	Positive	p < 0.01	6

T019003. F1 subunits
T019003003. ATP synthase subunit alpha, mitochondrial
T019003004. ATP synthase subunit beta, mitochondrial
T020. ATP